A study on the effect of proton pump inhibitors on the intragastric pH for the patients of functional dysplasia

A study on the effect of proton pump inhibitors on the intragastric pH for the patients of functional dysplasia - A study on the effect of proton pump inhibitors on the intragastric pH for the patients of functional dysplasia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003127

Enrollment

Registered

2010-02-15

Start date

2010-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functional dyspepsia(FD)

Interventions

Rabeprazole 10 mg before breakfast for 4 weeks Rabeprazole 20 mg before breakfast for 4 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Diagnosis of Functional Dyspepsia by Rome3 criteria 2. subjects with written informed consent

Exclusion criteria

Exclusion criteria: 1. Organic disease such as reflux esophagitis (> grade A) and erosive gastritis. 2. Patients with past history of gastrectomy 3. NSAIDs or low-dose aspirin -related dyspepsia 4. Patients with organic disease in the brain or with psychological disorders 5. Patients in psychiatric clinic 6.Patients with alcoholics or with drug dependence 7. Severe endocrine disease including hyperthyroidism 8. Severe diseases in heart, liver and kidney. Severe infectious or hemotological diseases 9. Drug allegy for rabeprazole 10. expectant mother, mother with breast-feeding 11. other not applicable person recognized by a doctor

Design outcomes

Primary

Measure	Time frame
evaluation of the gastric pH pre and post 4 weeks treatment with PPI	—

Secondary

Measure	Time frame
evaluation of the symptom index (GOS scale) pre and post 4 weeks treatment with PPI	—

Countries

Japan

Contacts

Public ContactKenji Furuta

Shimane University Faculty of Medicine School of Medicine Deaprtment of Gastroenterology

0853-20-2190

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026