the recurrence of endometriosis after laparoscopic surgery
Conditions
Interventions
One cycle regimen (7 weeks) consists of a consecutive administration of 1 mg of dienogest twice a day for 6 weeks followed by the rest for a week. The cycled regimen will be continued for a year.
One
Sponsors
Juntendo University faculty of medicine department of OB/GY
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Fifty patients with recurrent endometriosis after laparoscopic surgery who met the following inclusion criteria in our facility were enrolled. Written informed consent was obtained from all patients. 1) Patients with histologically proven endometriosis at the first surgical examination 2) Patients without histologically proven adenomyosis at the first surgical examination 3) Patients with recurrent endometriosis related pain, such as dysmenorrhea, dyspareunia, dyschezia, and the degree of the recurrent pain is the same as that of before surgery.
Exclusion criteria
Exclusion criteria: 1) Patients with undiagnosed genital bleeding 2) Pregnant women or possibly pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.During the observation period, the degree of pain will be evaluated by visual analogue scale (VAS) using medical examination by interview 2.During the observation period, the pattern of genital bleeding will be evaluated using medical examination by interview 3.The degree of pain and the degree of genital bleeding during the rest period will be evaluated using medical examination by interview | — |
Secondary
| Measure | Time frame |
|---|---|
| In patients with recurrent ovarian chocolate cyst, change in diameter of the ovarian chocolate cyst during the observation period will be evaluated. | — |
Countries
Japan
Outcome results
None listed