GERD patients
Conditions
Interventions
Oral administration of rikkunshito (2.5g t.i.d) before meals for 56 days
Sponsors
Chiba University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Selection criterion at enrollment 1) Patients who were diagnosed as having GERD according to endoscopic testing and the score (4 points or more) obtained on the questionnaire for the diagnosis of reflux disease (QUEST) 2) Patients with the upper gastrointestinal symptoms such as abdominal pain or dyspepsia 3) Patients who have signed consent to participate in this research
Exclusion criteria
Exclusion criteria: 1) Patients with severe cardiac failure, acute inflammatory disease or other severe complications 2) Patients who are pregnant, considering pregnancy or lactation 3) Patients with serious disorder in liver, gallbladder, or pancreas 4) Patients with gastrectomy 5) Patients who are intolerant to oral administration 6) Patients who received drugs prohibited for concomitant use during the observation period 7) Patients during treatment by traditional Japanese medicines 8) Patients considered inappropriate by the study investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of upper gastrointestinal symptoms in GERD patients | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Improvement of function of esophageal motility 2)Safety of rikkunshito | — |
Countries
Japan
Contacts
Public ContactToru Sato
Chiba University Hospital Department of Endoscopic Diagnostics and Therapeutics
Outcome results
None listed