Comparison of in vivo prophylactic activities of VICRYL* Plus and VICRYL*: Antimicrobial suture closure of thoracic drainage tube for lung cancer surgery: A phase II randomised study

Comparison of in vivo prophylactic activities of VICRYL* Plus and VICRYL*: Antimicrobial suture closure of thoracic drainage tube for lung cancer surgery: A phase II randomised study - Comparison of in vivo prophylactic activities of VICRYL* Plus and VICRYL*: Antimicrobial suture closure of thoracic drainage tube for lung cancer surgery

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003032

Enrollment

106

Registered

2010-01-14

Start date

2010-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

VICRYL PLUS* VICRYL*

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who agree with enrollment of this study Performance Status(ECOG Scale): 0 or 1 Patients suffer from lung cancer undergoing thoracotomy as curative surgey except for wedge resection White blood cell count > 3000/mm3 Noutrophilic leukocyte count > 1500/mm3 Platelet count > 75,000/mm3 Hemoglobin = or > 9.0g/dl AST(GOT)/ALT(GPT) = or <100 IU/L Total bilirubin = or < 2.0mg/dl PaO2 = or > 60Torr Creatinine clearance = or > 50ml/min [with Cockcroft-Gault method] or serum creatin level: within normal limits

Exclusion criteria

Exclusion criteria: Patients with pre-operative chemotherapy Patients with pre-operative radiation therapy Patients with former malignant disease as medical history

Design outcomes

Primary

Measure	Time frame
Wound infection rate	—

Secondary

Measure	Time frame
1 Wound dehiscence rate 2 Safety 3 Colonization rate on the wound and suture	—

Countries

Japan

Contacts

Public ContactTeruaki Mizobuchi

Graduate School of Medicine, Chiba University Department of General Thoracic Surgery

tmizobuchi@faculty.chiba-u.jp+81-43-222-7171

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026