The exploratory study for the efficacy of rikkunshito on anorexia in the patients with TS-1 treatment

The exploratory study for the efficacy of rikkunshito on anorexia in the patients with TS-1 treatment - The exploratory study for the efficacy of rikkunshito on anorexia in the patients with TS-1 treatment

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003014

Enrollment

Registered

2010-02-01

Start date

2010-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

Rikkunshito 7.5 g/day orally in 2 or 3 divided doses before meals for 6 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: At enrollment 1)The histologically confirmed gastric cancer patients who had received curative surgical procedure The patients adapting all follow criteria "Curability A or B" "No Serious postoperative complication" "ECOG PS grade 0, 1 or 2" 2)Planning TS-1 chemotherapy for postoperative adjuvant chemotherapy 3)The patients with written informed consent For starting test drug administration The patients with anorexia (CTCAE Grade 1 or 2) during TS-1 chemotherapy

Exclusion criteria

Exclusion criteria: 1)Severe complications (liver disorder, kidney disorder, heart disease, blood disease, metabolic disease etc) 2)Synchronous multiple cancer 3)Planning or during other chemotherapy 4)Disorder in liver, gallbladder, or pancreas 5)Gastrointestinal bleeding, mechanical ileus, gastrointestinal perforation 6)Planning or during treatment of investigational drug 7)Pregnant, considering pregnancy or lactation 8) Planning or during treatment of traditional Japanease medicine 9) As determined by the investigator the subject is not adequate to participate

Design outcomes

Primary

Measure	Time frame
Improvement of anorexia	—

Countries

Japan

Contacts

Public ContactKoji Yakabi

Saitama Medical Center, Saitama Medical University Department of Gastroenterology and Hepatology

kjyakabi@saitama-med.ac.jp049-228-3741

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026