corneal perforations, glaucoma, Recurrent pterygium
Conditions
Interventions
The patients with corneal perforations receive a single layer patch of the dried amniotic membrane using tissue adhesive in the minor procedure room under topical anesthesia with 2% lidocaine. The dri
Sponsors
Toyama University Hospital
Takaoka city hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Cause unknown corneal perforation Traumatic corneal perforation Corneal perforation related to collagen diseases Bleb leaks after glaucoma surgery Bleb failure due to unsuccessful glaucoma surgery <recurrence pterygium> The patients who had a diagnosis of the refractory eyes surface disease that at least one eye (target eyes) packed all the following criteria. In addition, the case same with an eye of the good few visions a binocular a few vision does oculus dexter with an efficacy evaluation eye when both eyes pack all the following criteria.Assume a fellow eye a control. 1) age:The patients who relatively have good Patient 2) overall status of (at the agreement acquisition) 20 years old or older 3)The patients whom pathologic proliferative tissue invaded in recurrent pterygium across limbus. 4)The patients whom it is judged to be available for observation, the testing that conformed to a study enforcement plan and a survey
Exclusion criteria
Exclusion criteria: Acute obvious ocular infectious signs are excluded. Exp. 1) Acute phase of bacterial, mycotic, or viral corneal ulcers 2) Acute phase of infectious bleb <recurrence pterygium> 1) onset pterygium patient or pseudopterygium patients. 2)The patients whom a doctor judged safely for 2) study period if it was difficult hospital visiting and to come home. 3)The patients who complicate eye infection with 3) activity. 4)The patients who plan the enforcement of eye operations for evaluation eyes effective during 4) study period in (we assume the agreement acquisition study initiation). 5)one eyes are the patients of enucleation eyes or evisceration eyes. 6)For the group medicine of the planned drug (dropping lotion in the eyes anesthetic agent, fluorescein) to use during 6) study period, it is the patients with a history of the drug allergy. 7)The patients (saying that, however, the subjects who do not receive the study drug are possible) who participated in other studies or clinical studies within six months. 8)The patients whom a doctor judged as an object of this study in testing at pregnancy or 9 childbearing patients) agreement acquisition that we might be pregnant or hoped for pregnancy during study period or did not use appropriate contraception for if inadequate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)visual acuity,2)intraocular pressures,3)Slit-lamp examinations including fluorescein dye staining,4)Ocular examinations by Anterior segment OCT | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of corneal thickness by corneal pachymeter. | — |
Countries
Japan
Contacts
Public ContactAtsushi Hayashi
University of Toyama Department of Ophthalmology
Outcome results
None listed