Musculoskeletal ambulation disability symptom complex (MADS) and underlying disorders of MADS
Conditions
Interventions
Participants will do a trial fitting of HAL 2 or 3 times a week for 2 weeks and then conduct exercises with HAL 2 or 3 times a week for 8 weeks.
Sponsors
University of Tsukuba
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Subjects must satisfy the following conditions for inclusion: 1. Need assistance from another person or aid in at least one of the following daily activities; standing up, sitting down, and walking. 2. Understand the explanation of the experiment and express consent or refusal. Informed consent will also be obtained from the patient's guardian if the patient is younger than 20 years. 3. Have a body shape that can be fitted into HAL. 4. Be able to undergo usual physical therapy and occupational therapy.
Exclusion criteria
Exclusion criteria: The following patients will be excluded: 1. Patients with inadequately treated cardiovascular disorders. 2. Patients with inadequately treated respiratory disorders. 3. Patients with intellectual impairments that interfere with their understanding of the explanetion of the experiment or instructions they need to follow. 4. Patients with moderate to severe articular problem, including contracture in the lower extremities. 5. Patients with a moderate to severe degree of involuntary movements, ataxia, or impairment of postural reflex in the trunk or lower extremities. 6. Patients with severe spasticity in the lower extremities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Balancing and walking ability will be evaluated with the Functional Balance Scale, the 10-m walking test, and the 3-m timed up and go test. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Vital signs (heart rate and blood pressure) 2. Severity of the disorder 3. Activities of daily living (Barthel Index) 4. Health-related quality of life (SF-36) 5. Profile of mood states (POMS) 6. Range of motion of the joints in the lower extremities 7. Muscle strength of the major muscles in the lower extremities 8. Rate of perceived exertion (Borg Scale) 9. Muscle action potentials 10. Satisfaction with the assistance in mobility provided by HAL 11. Amount of time needed to put on and take off the apparatus 12. Sabilometry 13. Functional MRI images of the brain 14. Three-dimensional motion analysis 15. Adverse events | — |
Countries
Japan
Contacts
Public ContactKiyoshi Eguchi
Faculty of Medicine, University of Tsukuba Division of Clinical Medicine
Outcome results
None listed