Keratoconus, keratectasia
Conditions
Interventions
Collagen fibers of the corneal stroma will be crosslinked by the combination of instillation of riboflavin solution and ultraviolet-A irradiation for 30 minutes after corneal epithelial debridement.
Sponsors
Department of Ophthalmology, Keio University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Keratoconus or keratectasia 2. The most thinnest corneal thickness more than 400 micrometer 3. In cases with keratoconus, progression should be observed within recent 6 months. In cases with keratectasia, protrusion of the cornea should be progressed after the previous corneal refractive surgeries.
Exclusion criteria
Exclusion criteria: 1. The corneal thickness less than 400 micrometer 2. Those who implanted medical instruments, such as pacemaker. 3. Ocular diseases, such as infection, corneal scar, herpetic keratitis, and/or nystagmus 4. Systemic diseases affecting corneal would healing 5. Eyes with narrow angle. Pregnant or breast-feeding women. 6. Occupation, by which refractive surgery is not arrowed
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual acuity, refraction, corneal curvature, corneal topography, corneal endothelial cell counts, and incidence of complications | — |
Countries
Japan
Contacts
Public ContactNaoko Kato
Keio University School of Medicine Department of Ophthalmology, Refractive Surgery Clinic
Outcome results
None listed