The study comparing ezetimibe with pravastatin on expressions and activities of small GTP-binding proteins, and on endothelial function.

The study comparing ezetimibe with pravastatin on expressions and activities of small GTP-binding proteins, and on endothelial function. - The study comparing ezetimibe with pravastatin on expressions and activities of small GTP-binding proteins, and on endothelial function.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000002946

Enrollment

Registered

2009-12-28

Start date

2009-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atherosclerotic cardiovascular diseases

Interventions

Ezetimibe(10mg/day) Pravastatin(10mg/day)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy individual

Exclusion criteria

Exclusion criteria: Pregnant or possibly pregnant individuals.

Design outcomes

Primary

Measure	Time frame
Expressions and activities of small-GTP binding proteins FMD(flow-mediated dilation)	—

Secondary

Measure	Time frame
Serum total and LDL cholesterol Serum triglyceride Cholesterol absorption and synthesis markers Adiponectin High sensitive CRP	—

Countries

Japan

Contacts

Public ContactKotaro Nochioka

Tohoku university graduate school of medicine Department of cardiovascular medicine

nochioka@cardio.med.tohoku.ac.jp022-717-7153

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026