Efficacy of BCAA food additional intake added to dosage of medicine made of BCAA

Efficacy of BCAA food additional intake added to dosage of medicine made of BCAA - Efficacy of BCAA food addition intake in BCAA replenishment treatment

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000002888

Enrollment

Registered

2009-12-14

Start date

2009-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

decompensated cirrhosis

Interventions

Medicine made of BCAA granules (4.0g) is taken 12 weeks continuously three times a day. In addition, the BCAA supplementation (3.2g) is taken as late evening snack every day. Medicine made of BCAA gr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Decompensated cirrhosis 2. The dietary intake is possible. 3. Hypoalbuminemia 4. Patients who give documentary informed consent voluntarily 5. Patient who fills all of the above-mentioned 1-4

Exclusion criteria

Exclusion criteria: 1. Patient who doesn't belong to application object of LIVACT 2. Patient who has the past of hepatic encephalopathy 3. Patient who has allergy in element of AMINOFEEL 4. The dietary intake is not enough in anorexia etc. , and the serum albumin is patients who decreased 0.1mg/dL or more in the past two months. 5. Patient who has infectious disease that becomes problem in clinical 6. Patient with serious glucose intolerance, respiratory failure and renal failure 7. Patient inappropriate for participating to this study decided by the attending physicians

Design outcomes

Primary

Measure	Time frame
Serum BTR (branched chain amino acids / tyrosine molar ratio) and serum albumin revel after 12 weeks from the beginning of the dairy branched-chain amino acid supplementation intake	—

Secondary

Measure	Time frame
Quality of Life(SF-36) and Urinary 8-OHdG(8-Hydroxydeoxyguanosine) excretion after 12 weeks from the beginning of the dairy branched-chain amino acid supplementation intake	—

Countries

Japan

Contacts

Public ContactMasaki Saito

Hyogo College of Medicine Division of Hepatobiliary and Pancreatic Diseases

he-jishu@hyo-med.ac.jp0798-45-6472

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026