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Retrospective study for significance of polymorphisms of UGT1A1 for Irinotecan toxicities in advanced cancer patients who received Irinotecan chemotherapy

Retrospective study for significance of polymorphisms of UGT1A1 for Irinotecan toxicities in advanced cancer patients who received Irinotecan chemotherapy - Retrospective study of polymorphisms of UGT1A1 and Irinotecan toxicities

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000002884
Enrollment
90
Registered
2010-01-25
Start date
2010-01-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

advanced cancer

Interventions

None listed

Sponsors

Tohoku University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Advenced cancer patients who received Irinotecan containing chemotherapy

Exclusion criteria

Exclusion criteria: n/a

Design outcomes

Primary

MeasureTime frame
Severe adverse effects of grade 3 or severer neutropenia and/or diarrhea after receiving Irinotecan containing chemotherapy

Countries

Japan

Contacts

Public ContactShoko Akiyama

Tohoku University Hospital Clinical Oncology

s-ikeda@idac.tohoku.ac.jp022-717-8543

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026