Association of HLA-DR gene polymorphism and rheumatoid arthritis associated genes (PADI4 and IRF5 polymorphisms) with juvenile idiopathic arthritis.

Association of HLA-DR gene polymorphism and rheumatoid arthritis associated genes (PADI4 and IRF5 polymorphisms) with juvenile idiopathic arthritis. - Association of HLA-DR gene polymorphism and rheumatoid arthritis associated genes (PADI4 and IRF5 polymorphisms) with juvenile idiopathic arthritis.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000002864

Enrollment

200

Registered

2009-12-10

Start date

2009-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

juvenile idiopathic arthritis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients with juvenile idiopathic arthritis treated in our hospital and with obtained prior written informed consent from patients and/or their parents.

Exclusion criteria

Exclusion criteria: The patient judged as improper case for enrollment in this study

Design outcomes

Primary

Measure	Time frame
Prevalence of juvenile idiopathic arthritis	—

Secondary

Measure	Time frame
Subgroup analysis based on (1) subtype of JIA (systemic onset or oligoarticular/polyarticular onset), (2) response to therapy, (3) the level of anti-citrullinated peptide antibodies, rheumatoid factor, antinuclear antibody, or matrix metalloproteiase-3, (4) family history of rheumatic disease and autoimmune disease,(5) complications such as macrophage activation syndrome and uveitis	—

Countries

Japan

Contacts

Public ContactMasakatsu Yanagimachi

Yokohama City University School of Medicine Department of Pediatrics

045-787-2671

Outcome results