Development of new positioning system in stereotactic irradiation for the brain tumor by linac-mounted cone-beam CT with contrast media administration

Development of new positioning system in stereotactic irradiation for the brain tumor by linac-mounted cone-beam CT with contrast media administration - Development of new positioning system in stereotactic irradiation for the brain tumor by linac-mounted cone-beam CT with contrast media administration

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000002836

Enrollment

Registered

2009-12-04

Start date

2009-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

metastatic brain tumor

Interventions

The patient is setup by registration of kilovoltage cone-beam CT under contrast media administration to the planning CT.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Metastatic brain tumors with maximum size of < 3 cm and less than 3 lesions Histopathological confirmation of malignancy in the primary site No history of intracranial irradiation Tumors enhanced by contrast media administration Laboratory tests within 28 days before accrual 1. WBC >= 4,000/mm3 and < 12,000/mm3 2. Neutrophil >= 2,000/mm3 3. Platelet >= 50,000/mm3 4. Hb >= 8.0 g/dl 5. Cre <= 1.1 mg/dl 6. expected Ccr >= 50ml/min (Cockcroft-Gault) PS 0-2, or PS3 due to the neurologic symptoms by brain tumor Age >= 20 Written informed consent

Exclusion criteria

Exclusion criteria: Active multiple cancer Women with pregnancy or with intent or possibility of pregnancy Chemotherapeutic agent (excluding hormone therapy) administered within 14 days Chronic renal failure requiring medical intervention Difficulty in application of head fixation shell History of an allergic reaction to iodine contrast media History of asthma Other conditions inappropriate for accrual

Design outcomes

Primary

Measure	Time frame
Setup error at the positioning	—

Countries

Japan

Contacts

Public ContactHiroshi Igaki

Teikyo University Hospital Department of Radiology

03-3964-1211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026