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The Effectiveness of Therapeutic Barium Enema for Prevention of Colonic Diverticular Rebleeding - Randomized Control study

The Effectiveness of Therapeutic Barium Enema for Prevention of Colonic Diverticular Rebleeding - Randomized Control study - The Effectiveness of Therapeutic Barium Enema for Prevention of Colonic Diverticular Rebleeding - Randomized Control Study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000002832
Enrollment
50
Registered
2009-12-02
Start date
2009-11-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colonic diverticular bleeding

Interventions

Barium therapy(intervention) Period of study for the enrolled: 12 months Follow-up: 12months Total period: 24 months Amount and concentration: 400ml, 200w/v% Number of times: one Conseravat

Sponsors

International Medical Center of Japan
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patient informations are as follows 1.nationality: Japanese 2.inpatient 3.Patients with independence in activities of daily living 4.Patients with painless hematochezia in abdomen 5.patients who was diagnosed with colonic diverticular bleeding from imaging test including CT or endoscopy 6.Patients with success of initial therapy (hemostasis) in colonic diverticular bleeding

Exclusion criteria

Exclusion criteria: Patient informations are as follows 1.Patients who does not provide consent 2.Patients who was diagnosed with other intestinal bleeding such as colon cancer, hemorroids with bleeding, upper gastrointestinal bleeding, and small-bowel bleeding 3.Patients with little improvement of hemostasis by initial therapy 4.Patients with hemorrhagic shock or with suspected hemorrhagic shock 5.Patients with allergic reaction to contrast dye incuding CT and barium examination 6.Patients with suspected intestinal obstruction on the X-ray 7.Patients with a history of barium therapy within 6 months 8.Patients with terminal cancer 9.Patients with difficulty in changing body position 10.Patients with suspected pregnancy 11.Patients with a history of colon resection 12.Patients with already revealed intestinal cancer 13.Patients with diagnosis of imflammatory bowel disease(IBD)

Design outcomes

Primary

MeasureTime frame
The rate and period until diverticular rebleeding after the treatment with barium and conservative therapy

Secondary

MeasureTime frame
clinical data between rebleeding and non-rebleeding patients: age, sex, underlying disease, history of medication, and volume of transfusion. clical data on barium therapy: the finding of X-ray, examination time, and complication.

Countries

Japan

Contacts

Public ContactNaoyoshi Nagata

International Medical Center of Japan Gastroenterology

nnagata_ncgm@yahoo.co.jp03-3202-7181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026