Evaluation of preventive effect of tranilast on esophageal stricture after extensive endoscopic submucosal dissection (ESD) therapy for superficial esophageal cancer.

Evaluation of preventive effect of tranilast on esophageal stricture after extensive endoscopic submucosal dissection (ESD) therapy for superficial esophageal cancer. - Preventive effect of tranilast on esophageal stricture after ESD

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000002741

Enrollment

Registered

2010-01-01

Start date

2009-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

superficial esophageal cancer

Interventions

tranilast placebo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who undergo extensive ESD (more than 2/3 circumference) for superficial esophageal cancer.

Exclusion criteria

Exclusion criteria: Patients who requires additional treatments such as radiation or operation due to deep invasion of esophageal cancer.

Design outcomes

Primary

Measure	Time frame
The numbers of balloon esophageal dilation required for the post-treatment stricture & patients' symptoms	—

Countries

Japan

Contacts

Public Contactiijima Katsunori

Tohoku University Hospital Division of Gastroenterology

jiijima@int3.med.tohoku.ac.jp

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026