Glaucoma Ocular Hypertension
Conditions
Interventions
After more than 4weeks of washout period, instill Tafluprost for 8 weeks. Then 4 weeks of second washout period, instill Latanoprost for 8weeks.
After more than 4weeks of washout period, instill Latan
Sponsors
Kyoto University Hospital Department of Ophthalmology and visual sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Diagnosed with primary open angle glaucoma or ocular hypertension, and being receiving monotherapy or no-treatment. 2) Intraocular pressure is more than 16 mmHg without treatment or more than 13 mmHg with monotherapy treatment. 3) Over 20 years old on the date of agreement. 4) Both male and female 5) Outpatient care 6) Subjects whose agreement was shown by him/herself.
Exclusion criteria
Exclusion criteria: 1) Having any hypersensitivity to test drugs. 2) Having severe visual field defect (HFA <-15dB) 3) Having absolute scotoma within 5 degrees in the center of the visual field. 4) Having any corneal abnormality or other condition preventing reliable applanation tonometry. 5) Having history of glaucoma surgery. 6) Having history of cataract surgery within 1 year. 7) Having history of refractive surgery. 8) Presence of any external ocular disease, inflammation or infection of the eye and/or eyelids. 9) Subjects need to be treated with corticosteroid during study period. 10) Pregnant subjects and subjects suspected of being pregnant 11) Subjects investigators declare ineligible for any sound medical reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy: Intraocular Pressure Lowering rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraocular Pressure Safety | — |
Countries
Japan
Contacts
Public ContactAtsushi Nonaka
Kyoto University Hospital Department of Ophthalmology and visual sciences
Outcome results
None listed