Endothelial Dysfunction Assessed by Reactive Hyperemia Peripheral Arterial Tonometry and Heart Failure with Preserved Left Ventricular Ejection Fraction

Endothelial Dysfunction Assessed by Reactive Hyperemia Peripheral Arterial Tonometry and Heart Failure with Preserved Left Ventricular Ejection Fraction - Endothelial Dysfunction Assessed by RH-PAT and Heart Failure with Preserved LVEF

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000002640

Enrollment

500

Registered

2009-10-21

Start date

2006-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart failure with normal left ventricular ejection fraction

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with normal left ventricular ejection fraction (EF>50%) and the control patients reactive hyperemia peripheral artery tonometry was performed

Exclusion criteria

Exclusion criteria: Acute coronary syndrome Severe valvular disease Hypertrophic obstructive cardiomyopathy Coronary spastic angina Severe collagen disease malignant disease Hemodialysis

Design outcomes

Primary

Measure	Time frame
Peripheral endothelial function Composite endopoint of cardiovascular death, non-fatal myocardial infarction, unstable angina pectoris, non-fatal ischemic stroke, re-hospitalization for HF, or coronary revascularization	—

Secondary

Measure	Time frame
NYHA classification	—

Countries

Japan

Contacts

Public ContactSeigo Sugiyama

Graduate School of Medical Sciences, Kumamoto University Department of Cardiovascular Medicine

ssugiyam@kumamoto-u.ac.jp81-96-373-5175

Outcome results