Antidepressant mechanism of repetitive transcranial magnetic stimulation in treating medication-resistant depression

Antidepressant mechanism of repetitive transcranial magnetic stimulation in treating medication-resistant depression - Antidepressant and antinociceptive mechanism of repetitive transcranial magnetic stimulation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000002541

Enrollment

Registered

2009-09-24

Start date

2008-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depression who were resistant to antidepressants

Interventions

repetitive transcranial magnetic stimulation for medication-resistant depressives no treatment in normal controls

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Major depressive disorder and a history of medication resistance (> 2 kinds of antidepressants failures)

Exclusion criteria

Exclusion criteria: Major systemic illness. Bipolar disorders. Cluster B personality. OCD and PTSD.

Design outcomes

Primary

Measure	Time frame
to see if neurobiological singals from multiple neuroimaging modalities could differentiate rTMS responders from non-responders	—

Secondary

Measure	Time frame
to study neural correlates of rTMS antinociceptive effects	—

Countries

Asia(except Japan)

Contacts

Public ContactCheng-Ta Li

Taipei Veterans General Hospital,Taiwan Psychiatry Department

cheng-ta.li@nih.gov

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026