Skip to content

Endoscopic Ultrasound-guided Celiac Plexus Neurolysis vs Direct Celiac Ganglia Neurolysis for upper abdominal cancer pain: A randomized multicenter phase-II trial

Endoscopic Ultrasound-guided Celiac Plexus Neurolysis vs Direct Celiac Ganglia Neurolysis for upper abdominal cancer pain: A randomized multicenter phase-II trial - EUS-CPN vs EUS-CGN for cancer pain

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000002536
Enrollment
62
Registered
2009-10-01
Start date
2009-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper abdominal cancer pain

Interventions

EUS-CPN EUS-CGN

Sponsors

EUS-CPN/CGN study group
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. Patients with upper abdominal malignancy whose diagnosis was confirmed by pathological or imaging results. 2. Patients with upper abdominal or back pain of grade-4 or more visual analog scale (VAS) score. 3. Patients with relatively good performance status, ECOG PS 3 or less.

Exclusion criteria

Exclusion criteria: 1) Patients whose informed consent could not be obtained. 2) Patients with lack of communication ability. 3) PT-INR: >= 1.5. 4) Platelet count: <=50,000/mm2. 5) Regularly user of anti-coagulants, and in case that the administration cannot be suspended. 6) Patients with esophageal or cardia varices. 7) Patients with severe alcohol intolerance. 8) In case that doctors judged inappropriate for the entry to this study.

Design outcomes

Primary

MeasureTime frame
Pain relief effect at 7 days after the treatment (ratio of effective cases)

Secondary

MeasureTime frame
Ratio of complete pain relief cases at 7 days after the treatment, Difference of VAS between before and 7 days after the treatment, duration of pain relief effect, procedure period, and incidence of complications.

Countries

Japan

Contacts

Public ContactIchiro Yasuda

Gifu University Hospital First Dept. of Internal Medicine

YASUDAIC@aol.com058-230-6308

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026