non-squamous,non-small cell lung cancer
Conditions
Interventions
pemetrexed
Sponsors
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Histologically or cytologically proven non-squamous non-small cell lung cancer 2)patients with stage IIIB or stage IV, who is impossible of radical irradiation 3)Non prior chemotherapy and irradiation for any other carcinomas.But we can permit picibani and minocycline for a pleurodesis. 4)With measurable lesion 5)20 years or older 6)ECOG PS 2 7)Adequate organ function 8)Life expectancy more than 12 weeks 9)Written informed consent
Exclusion criteria
Exclusion criteria: 1)Interstitial pneumonia or pulmonary fibrosis detectable on Xray 2)History of severe drug allergy 3)History of poorly controlled pleural effusion,pericardial effusion and ascites.When that is controlled,we can permit. 4)History of symptomatic brain metastases 5)Hystory of active double cancer 6)History of severe comorbidity disease i)uncontrollable angina pectoris,herat failure) ii)active infection 7)History of active psychological disease 8)Pregnancy,breast feeding or wish of future bearing 9)with systemic continuous steroid therapy 10)Other conditions not suitable for this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-free survival,Overall survival,QOL | — |
Countries
Japan
Contacts
Public Contactyuichi sakamori
Graduate School of Medicine, Kyoto University Department of Respiratory Medicine
Outcome results
None listed