Investigation on permeability of the round window and size of the membranous labyrinth with use of intratympanic gadolinium administration

Investigation on permeability of the round window and size of the membranous labyrinth with use of intratympanic gadolinium administration - Magnetic resonance imaging after intratympanic gadolinium administration

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000002482

Enrollment

175

Registered

2009-09-11

Start date

2006-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hearing loss or vertigo due to inner ear diseases

Interventions

Intratympanic gadolinium administration through the tympanic membrane

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with intractable sudden deafness before intratympanic steroid injection. Patients with suspected Meniere's disease. Patients with intractable Meniere's disease before intratympanic gentamicin therapy.

Exclusion criteria

Exclusion criteria: Patients with otitis media.

Design outcomes

Primary

Measure	Time frame
Presence or absence of the endolymphatic hydrops Degree of the endolymphatic hydrops Permeability of the round window membrane Adverse effect	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026