Prospective study of stereotactic body radiotherapy for small lung lesions clinically diagnosed as primary lung cancer without pathologic confirmation

Prospective study of stereotactic body radiotherapy for small lung lesions clinically diagnosed as primary lung cancer without pathologic confirmation - Prospective study of stereotactic body radiotherapy for small lung lesions clinically diagnosed as primary lung cancer without pathologic confirmation

Status

Active, not recruiting

Phases

Phase 2

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000002458

Enrollment

Registered

2009-09-08

Start date

2009-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary lung cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with lung tumor less than 3cm in diameter and less than three lesions. 2) Patients unable to confirm pathological diagnosis. 3) Positive on FDG-PET except patients with GGO. 4) Apparent growth of lung tumor on CT. 5) Aged 20 years or more, 0-2 of ECOG performance status. 6) Patients must be consulted by surgeon. 7) Patients must be consulted by internal physician. 8) Able to make planning of radiotherapy within the regulation dose. 9) No history of radiation for chest. 10) PaO2 60 torr or more at room air, FEV1.0 700 ml or more.

Exclusion criteria

Exclusion criteria: 1) Apparent interstitial pneumonia on chest X-ray. 2) Patinets with active infectious disease. 3) Patients with active other cancers. 4) Pregnant patients. 5) Patients with psychiatric disorders and unable to participate the study. 6) Patients now treated by steroids. 7) Patients who need oxygen inhalation. 8) Fever up.

Design outcomes

Primary

Measure	Time frame
overall survival rate	—

Secondary

Measure	Time frame
progression-free survival rate, safety	—

Countries

Japan

Contacts

Public ContactTetsuya Inoue

Hokkaido University Graduate School of Medicine Department of Radiology

t-inoue@med.hokudai.ac.jp011-706-5977

Outcome results