Prefrontal reactivity in mood disorders during repetitive transcranial magnetic stimulation.

Prefrontal reactivity in mood disorders during repetitive transcranial magnetic stimulation. - Prefrontal reactivity in mood disorders during repetitive transcranial magnetic stimulation.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000002437

Enrollment

Registered

2009-09-03

Start date

2004-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

major depressive disorder, bipolar disorder

Interventions

The low frequency repetitive transcranial magnetic stimulation to the right prefrontal cortex. sham stimulation.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients with MDD and BD were diagnosed in accordance with the criteria in the Diagnostic and Statistical Manual of Mental Disorders, 4th ed.

Exclusion criteria

Exclusion criteria: The exclusion criteria was strictly followed the report and suggested guidelines from the International Workshop on the Safety of Repetitive Transcranial Magnetic Stimulation by Wassermann.

Design outcomes

Primary

Measure	Time frame
To monitor the regional cerebral blood volume changes using multichannel near-infrared spectroscopy.	—

Secondary

Measure	Time frame
Clinical symptoms of the patients were evaluated using the 24-item Hamilton Rating Scale for Depression, and the level of social functioning of all the subjects were assessed using the Global Assessment of Functioning scores.	—

Countries

Japan

Contacts

Public ContactYoshiyuki Aoyama

Gunma University Graduate School of Medicine Department of Psychiatry and Neuroscience

yaoyama@med.gunma-u.ac.jp027-220-8188

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026