Cough variant asthma
Conditions
Interventions
Inhale Salmeterol/fluticasone propionate combination 250 mcg twice daily
Inhale Fluticasone propionate 200 mcg twice daily, and take Montelukast 10 mg once daily
Sponsors
Kyoto University Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Couth variant asthma patients 2)Patients who are still poorly controlled despite monotherapy with inhaled corticosteroids 3)Patients who gave consent to the study
Exclusion criteria
Exclusion criteria: 1)Patients without cough symptom in the last 1 week before enrollment 2)Patients with other respiratory diseases 3)Patients taking Long acting be-ta 2 agonist(LABA) or Leukotriene receptor antagonist(LTRA) 4)Patients who are given systemic corticosteroid in the last 4 weeks 5)Patients who suffered from upper respiratory infection in the last 4 weeks 6)Patients who had smoked in the last 6 months, or who had smoked more than 10 pack year in the past 7)Patients who are considered inappropriate by physicians in charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analogue scale score of cough | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Parameters of impulse oscillometry 2)Indices of pulmonary function 3)Indices of Capsicine cough sensitivity 4)Exhaled nitric oxide concentrations 5)Biomarker levels of induced sputum 6)Biomarker levels of serum and urine 7)Scores of questionnaires | — |
Countries
Japan
Contacts
Public ContactTomoko Tajiri
Kyoto University Graduate School of Medicine Department of Respiratory Medicine
Outcome results
None listed