non-small-cell lung cancer
Conditions
Interventions
Adjuvant chemotherapy of eight courses (2-week administration and 1-week withdrawal): S-1 dose of 67mg/m2 twice daily
Sponsors
Lung Oncology Group in Kyushu, Japan (LOGIK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Histologically confirmed NSCLC 2)p-Stage IB, II and III & complete resection 3)No prior treatment 4)Adjuvant chemotherapy within 4-8 weeks 5)ECOG PS 0-1 6)Age 70 or older 7)Adequate organ function 8)Written informed consent
Exclusion criteria
Exclusion criteria: 1)Past history of drug hypersensitivity 2)Past history of myocardial infarction within 6 months 3)Interstitial pneumonia or active lung fibrosis 4)Uncontrolled heart diseases 5)Uncontrolled psychiatric disorders 6)Uncontrolled diabetes 7)Bowel problems 8)Active infection 9)Severe complications 10)Active concomitant malignancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The percentage of patients who accomplished S-1 therapy of eight courses. | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events The relative total administration dose of S-1 | — |
Countries
Japan
Contacts
Public ContactNoriyuki Ebi
Iizuka Hospital Department of respiratory medicine
Outcome results
None listed