To prevent low-dose aspirin induced peptic ulcers, which is better the use of proton pump inhibitors or histamine type2 receptor agonist; randomized controlled trial

To prevent low-dose aspirin induced peptic ulcers, which is better the use of proton pump inhibitors or histamine type2 receptor agonist; randomized controlled trial - To prevent low-dose aspirin induced peptic ulcers, which is better the use of PPI or H2RA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000002382

Enrollment

400

Registered

2009-09-04

Start date

2009-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

the patients who are taking low dose aspirin

Interventions

famotidine 40mg/day lansoprazole 15mg/day

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient who fills everything the following 1)Patients who are taking low-dose aspirin 2) Patient of 20 years or older and 90 years or younger 3) Patient who gives written informed consent

Exclusion criteria

Exclusion criteria: The patient who collides with either the following assumes that it doesn't put it in to the examination 1) Drug allergy 2)Patient who have taken PPI 3)Patient who have taken clopidogrel, antifungal agent, and corticosteroid 4)Patient who have malignant neoplasm 5)Patient who is postgastrectomy 6)pregnant and lactation 7)Liver disorder, renal disorder, bronchial asthma

Design outcomes

Primary

Measure	Time frame
with or without peptic ulcer on the patients who are taking low dose aspirin	—

Countries

Japan

Contacts

Public ContactMasahiko Inamori

Yokohama City University Graduate School of Medicine Gastroenterology Division

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026