Substudy of lipid lowering trial on prevention of atherosclerosis in 75 or older on cholesterol absorption and synthesis

Substudy of lipid lowering trial on prevention of atherosclerosis in 75 or older on cholesterol absorption and synthesis - EWTOPIA75-Kyushu

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000002292

Enrollment

1000

Registered

2009-08-10

Start date

2009-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyper-LDL-cholesterolemia

Interventions

ezetimibe and diet diet

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: same as EWTOPIA75

Exclusion criteria

Exclusion criteria: same as EWTOPIA75

Design outcomes

Primary

Measure	Time frame
0 to 24weeks (1)changes in cholesterol absorption and synthesis (2)changes in inflammation markers (3)changes in lipoproteins(RLPcholesterol, small dense LDL etc), oxydised phospholipid, oxdised cholesterol) (4)NT-proBNP	—

Secondary

Measure	Time frame
relation to composite cardiovascular events (same as EWTOPIA75)	—

Countries

Japan

Contacts

Public ContactJun Sasaki, MD.PhD

EWTO75-Kyushu group EWTOPIA-Kyushu group office

fukuoka-shiken@iuhw.ac.jp092-711-1126

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026