Pateients with type II diabetes combined with dyslipidemia
Conditions
Interventions
Ezetimibe and Statin
Sponsors
Department of Cardiovascular Medicine, Saga University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: For entry into the study, participants must meet all of the following criteria. 1) Type II diabetes 2) Dyslipidemia given statin drug over 3 months. 3) At the time of entry, ezetimibe is not taken. 4) Age: 20years or older 5) Gender: regardless 6) Outpatient/hospitalized: regardless 7) Agreements: capable of giving consent and written agreement.
Exclusion criteria
Exclusion criteria: 1) Pregnant and/or breathfeeding, child-bearing potential women during this study. 2) Past history of severe allergic reactions to ezetimibe 3) Renal dysfunctioned. (ALT>2 x Normal range of each institute) 4) Uncontrolled diabetes mellitus (HbA1c>=9%) 5) Renal insufficiency (serum creatinine>2.0mg/dL) 6) Heart failure, cardiac infarct, unstable angina, or stroke whithin 3 months. 7) Recieving insulin therapy 8) Secondary hyperlipidemia and/or drug-induced hyperlipidemia 9) Familial hyperlipidemia 10) otherwise, treating physician judged not to be appropriate for inclusion in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Examination of the rate change of glucouse metabolism and inflammatory marker Examination of ameliorating effect in kidney function | — |
Secondary
| Measure | Time frame |
|---|---|
| Examination of the rate change of TC, HDL cholesterol, and TG Decreasing rate of LDL cholesterol | — |
Countries
Japan
Contacts
Public ContactKoichi Node, MD, PhD
Saga University Department of Cardiovascular Medicine
Outcome results
None listed