endometrial cancer atypical endometrial hyperplasia
Conditions
Interventions
Patients were scheduled to received 400mg per day of medroxyprogesterone acetate with 100mg of aspirin orally on a daily basis for 24weeks. The metformin combines concurrently. We administer the m
Sponsors
chiba university
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: (1) Histrogically confirmed well differentiated endometrioid adenocarcinoma at presumed stage IA and atypical endometrial hyperplasia (2) myometrium invasion was ruled out by MRI (3)performance status of 0 to 1 (4) serum creatinine <1.0mg/dl (5) A case without hypersensitivity for this treatment use medicine (6) The case that written informed consent was obtained before participation
Exclusion criteria
Exclusion criteria: (1) The case with a history of the hypersensitivity that is serious for this study use medicine or the drug allergy (2)A history of the lactic acidosis (3)Patients on dialysis (4)Shock, failure heart, myocardial infarction, a cardiovascular injury including the pulmonary embolism (5)Excessive alcohol intake (6)Hepatic dysfunction (7) A history of the thrombosis (8)A case with the psychic disturbance that it seems that we need in the treatment or treatment with antimental medicine (9) Patients with diabetes (10)A case with the double cancer of the activity (11)In addition, the case that the chief physician judged to be inadequate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence free interval | — |
Secondary
| Measure | Time frame |
|---|---|
| Primary complete response rate Pregnancy rate Side effect | — |
Countries
Japan
Contacts
Public ContactAkira Mitsuhashi
Graduate School of Medicine, Chiba University Reproductive medicine
Outcome results
None listed