The analysis of effects on insulin resistance and atherosclerotic risk factors before and after the treatment in patients with primary aldosteronism (PA)

The analysis of effects on insulin resistance and atherosclerotic risk factors before and after the treatment in patients with primary aldosteronism (PA) - The analysis of insulin resistance and risk factors alterations by the treatment of PA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000002196

Enrollment

20

Registered

2009-07-14

Start date

2009-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary aldosteronism

Interventions

Surgical resection if PA is lateral adrenal tumor Eplerenone administration if PA is bilateral hyperplasia

Sponsors

Faculty of Life Sciences, Kumamoto University

Lead Sponsor

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Hypertension and 2) Aldosteron/renin ratio more than 20, and/or 3) Aldostreon/cortison rario more than 1.0 upon rapid ACTH loading test

Exclusion criteria

Exclusion criteria: Glucocorticoid-remediable aldosteronism (GRA)

Design outcomes

Primary

Measure	Time frame
1) Insulin resistance 2) Inflamatory cytokine 3) markers of organ damage	—

Countries

Japan

Contacts

Public ContactTatsuya Kondo

Faculty of Life Sciences, Kumamoto University Metabolic Medicine

t-kondo@gpo.kumamoto-u.ac.jp+81-96-373-5169

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026