Effects of antihypertensive therapy on platelet function and insulin sensitivity in patients with glucose intolerance

Effects of antihypertensive therapy on platelet function and insulin sensitivity in patients with glucose intolerance - Effects of antihypertensive therapy on platelet function and insulin sensitivity

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000002192

Enrollment

Registered

2009-07-13

Start date

2009-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients with glucose intolerance and hypertension

Interventions

antihypertensive therapy for 60d with calcium channel blocker(Amlodipine) antihypertensive therapy for 60d with angiotensin converting enzyme blocker (Enalapril) antihypertensive therapy for 60d with

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: non-treated patients having fasting plasma glucose level more than 100 mg/dl and systolic blood pressure more than 130 mmHg and diastolic blood pressure more than 80 mmHg

Exclusion criteria

Exclusion criteria: 1) patients having pregnancy, severe liver, kidney or heart disease 2) patients who have already treated with statin, biguanide or thiazolidine 3) patients who have a history of drug allergy

Design outcomes

Primary

Measure	Time frame
platelet aggregation	—

Secondary

Measure	Time frame
plasma glucose level, plasma IRI level	—

Countries

Japan

Contacts

Public ContactKazuo Kajita

Gifu University School of Medicine General Internal Medicine

kkajita@gifu-u.ac.jp058-230-6000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026