stable coronary heart disease patients with dyslipidemia
Conditions
Interventions
statin therapy
statin+EPA therapy
Sponsors
Center for Clinical Research, Yamaguchi University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: stable coronary heart disease with dyslipidemia (T-CHO>180 mg/dL, LDL-C 100mg/dL)
Exclusion criteria
Exclusion criteria: 1)myocardial infarction within 3 months 2)unstable angina 3)combined severe heart disease 4)post-cardiac intervention within 3 months 5)cerebrovascular disease within 3 months combined severe hepatic or renal disease 6)malignamcy 7)uncontrolled diabetes 9)secondary dyslipidemia 10)steroid-induced hyperlipidemia 11)familiar hypercholesterolemia 12)bleeding tendency 13)chronic atrial fibrillation 14)pregnancy or expected pregnancy 15)age 70 year-old and or over 16)peripheral artery diase (Fontane2 and more) 17)investigator-decided
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| relationship among oxidative stress and lipid profile, and aortic stiffness and carotid atherosclerosis | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)relationship between cardiovascular event and oxidative stress 2)relationship between inflammatory marker and aortic stiffness 3)relationship between coronary risk factors and oxidative stress | — |
Countries
Japan
Contacts
Public ContactSeiji Umemoto
Yamaguchi University Hospital Pharmaceutical clinical research center
Outcome results
None listed