A randomized controlled trial comparing anti-postoperative atrial fibrillation effect of landiolol hydrochloride in cardiac surgery for cardiac dysfunvtion

A randomized controlled trial comparing anti-postoperative atrial fibrillation effect of landiolol hydrochloride in cardiac surgery for cardiac dysfunvtion - PASCAL trial-II

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000002160

Enrollment

Registered

2009-07-03

Start date

2009-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myocardial infarction, angina, valvular disease

Interventions

intra-and perioperative administration of landiolol hydrochloride intra-and perioperative non-administration of landiolol hydrochloride

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Cardia operation patients from whom informed consent was obtained

Exclusion criteria

Exclusion criteria: past of arrhythmia sinus bradycardia at rest (<50/min) second -or third-degree AV block clinical hypothyroidism or hyperthyroidism Doctor's decision not to register to this regimen

Design outcomes

Primary

Measure	Time frame
incidence of postoperative atrial fibrillation	—

Secondary

Measure	Time frame
Cardiac event,MACCE Cardiac function (UCG) Blood pressure, heart rate, CVP BNP, CK-MB, Toronin, HFBP,hs-CRP	—

Countries

Japan

Contacts

Public ContactAkira Sezai

Nihon University School of Medicine

asezai.med@gmail.com03-3972-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026