Randomized controlled trial on an effect of preparation of botanical extract on physiological halitosis.

Randomized controlled trial on an effect of preparation of botanical extract on physiological halitosis. - Effect of preparation of botanical extract on physiological halitosis.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000002145

Enrollment

Registered

2009-08-01

Start date

2009-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Physiological halitosis

Interventions

Preparation of botanical extract group: During the 4 weeks, subjects eat two tablets of preparations five times per day (after three main meals, between one of the main meals and before bedtime). Plac

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subjects with physiological halitosis # Organoreptic score >=2 and total volatile sulfur compounds >=0.15 ppm # All periodontal probing depth of six teeth selected from the six areas <4mm # Mean gingival index <2 and mean plaque index <2

Exclusion criteria

Exclusion criteria: Subjects without physiological halitosis A history of systemic disease Antibiotic treatment or periodontal treatment within the previous 3 months

Design outcomes

Primary

Measure	Time frame
organoleptic score, measurement of volatile sulfur compounds in breath, periodontal pathogens in saliva	—

Countries

Japan

Contacts

Public ContactMuneo Tanaka

Osaka University Dental Hospital Department of Preventive Dentistry

06-6879-2922

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026