Benign prostatic hypertophy associated with overactive bladder
Conditions
Interventions
naftopidil 25mg to 75mg daily
tamsulosin 0.2mg daily
Sponsors
Department of Urology, the University of Tokyo Hospital
Nihon University, Bokutoh Hospital, Tokyo Kyosai Hospital, Police Hospital, Fraternity Memorial Hospital, Geriatric Hospital, Japan Red Cross Medical Center, Misato Kenwa Hospital
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. previously untreated cases with benign prostatic hypertrophy 2. prostatic volume>=20ml 3. IPSS total score>=8 and QOL score>=2 4. Question 2 of IPSS>=2 5. Question 4 of IPSS>=2
Exclusion criteria
Exclusion criteria: 1. residual volume>=50ml 2. cases with prostatic cancer, bladder cancer or interstitial cystitis 3. cases with urethral stricture 4. cases with diseases which may affect on the lower urinary tract symptoms such as diabate mellitus, cerebral vascular disease and spinal cord injury 5. cases with past history of allergic reaction to naftopidil or tamsulosin
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| frequency of voiding, maximum voiding volume, average voiding volume | — |
Primary
| Measure | Time frame |
|---|---|
| grade of desire for voiding measured by frequency volume chart | — |
Countries
Japan
Contacts
Public ContactHaruki Kume
the University of Tokyo Hospital Department of Urology
Outcome results
None listed