Patients with pain
Conditions
Interventions
Transdermal single administration of 30mg morphine
Transdermal single administration of 60mg morphine
Transdermal single administration of 90mg morphine
Transdermal single administration of 180mg morp
Sponsors
Department of Clinical Pharmacology and Therapeutics
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Cancer patients 2) Patients who have never treated with morphine 3) Patients who need opioid drugs including morphine
Exclusion criteria
Exclusion criteria: 1) Patients with severe respiratory disorder 2) Patients with bronchial asthma attack 3) Patients with severe liver dysfunction 4) Patients with heart failure associated with chronic lung disease 5) Patients with alcohol abuse 6) Patients susceptible with alkaloid
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pharmacokinetics of transdermal morphine | — |
Countries
Japan
Outcome results
None listed