Healthy volunteers
Conditions
Interventions
100mg D-cycloserine
400mg Valproic acid
100mg D-cycloserine with 400mg Valproic acid
placebo (inactive substance)
Sponsors
National Institute of Mental Health, National Center of Neurology and Psychiatry
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Healthy volunteers with informed consent
Exclusion criteria
Exclusion criteria: 1. Having previous histories of drug or alcohol abuse or of neurological, psychiatric, or physiological disorders. 2. Taking an OTC [over-the-counter] drug and/or supplement tablets regularly. 3. Who recognized as unsuitable for testing by physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Participants' physiological responses to the stimuli will be recorded. Electrodes will be placed on two fingers (to measure sweat, or electrodermal activity), on both wrists and a lower leg (to measure heart rate). | — |
Secondary
| Measure | Time frame |
|---|---|
| Accuracy and reaction time to tha memory tasks are also included as secondary ealuation outcomes. | — |
Countries
Japan
Contacts
Public ContactKenichi Kuriyama
National Institute of Mental Health, National Center of Neurology and Psychiatry Departments of Adult Mental Health
Outcome results
None listed