Clinical safety and efficacy of combination of sustained-release morphine and transdermal fentanyl patch to the dyspnea in lung cancer patients

Clinical safety and efficacy of combination of sustained-release morphine and transdermal fentanyl patch to the dyspnea in lung cancer patients - Clinical safety and efficacy of combination of sustained-release morphine and transdermal fentanyl patch to the dyspnea in lung cancer patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001958

Enrollment

Registered

2009-06-01

Start date

2009-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

administration of susteined-release morphine

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. diagnosed with lung cancer, announced that cancer patients 2. The patients age 20 or older 3. Patients are administered of transdermal fentanyl patch for cancer pains 4. Patients with dyspnea does not improve by including non-drug therapy, oxygen. 5. A consent of patients is obtained in writing and fully explain the effects and side effects

Exclusion criteria

Exclusion criteria: 1. Patients with severe cardiac dysfunction 2. Patients with severe renal or liver dysfunction 3. Patients with increased intracranial pressure 4. Patients with skin disorders such as atopic 5. Patients have a fever of more than 40 degree centigrade 6. Patients with impaired consciousness 7. Other than the orally drug (suppository drug and injection) is administered to patients by drug route of morphine

Design outcomes

Primary

Measure	Time frame
Improvement of dyspnea	—

Countries

Japan

Contacts

Public ContactAkihiro Sakashita

Kobe University Graduate School of Medicine Division of Respiratory Medicine, Department of Internal Medicine

meidai@med.kobe-u.ac.jp078-382-5846

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026