A study on measurement of KP-103 concentration in nails (Phase I) - Investigation of KP-103 concentration in nails following repeated topical application to toenails in patients with onychomycosis -

A study on measurement of KP-103 concentration in nails (Phase I) - Investigation of KP-103 concentration in nails following repeated topical application to toenails in patients with onychomycosis - - A study on measurement of KP-103 concentration in nails (Phase I)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001949

Enrollment

Registered

2009-05-08

Start date

2009-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Onychomycosis

Interventions

Once daily before bedtime KP-103 5% is applied each 2 drops to left and right first toenails and each one drop to all other toenails for 28 days. Once daily before bedtime KP-103 10% is applied each

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patient with onychomycosis in either left or right first toenail or both, as demonstrated by mycological examination (direct KOH microscopy) and clinical symptoms (2) With or without left or right second toenail affected with onychomycosis (3) All types and severity of onychomycosis (4) Patient who can personally provide written informed consent

Exclusion criteria

Exclusion criteria: (1) Patient on corticosteroid (except external preparation for topical action to areas other than toenails is allowable) (2) Patient with problems in safety

Design outcomes

Primary

Measure	Time frame
KP-103 concentration in nails, onset of adverse effects and their severity	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026