The clinical study for the mechanism of pioglitazone-induced edema in patients with type 2 diabetes using a salt monitoring system

The clinical study for the mechanism of pioglitazone-induced edema in patients with type 2 diabetes using a salt monitoring system - The clinical study for the mechanism of pioglitazone-induced edema

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001948

Enrollment

Registered

2009-05-08

Start date

2006-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

administration of pioglitazone (15mg/day)

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Type 2 diabetic patients after obtaining written informed concent

Exclusion criteria

Exclusion criteria: 1) Congestive heart failure or having a history of congestive heart failure 2) Severe ketosis, diabetic coma, or type 1 diabetes 3) Having a severe hepatic or renal dysfunction 4) Having a severe infection or injury, or during perioperative period 5) Having an allergic history of pioglitazone 6) Be pregnant or at risk of becoming pregnant 7) Receiving any diuretic medication 8) Evaluated as being inadequate by the physician-in-charge

Design outcomes

Primary

Measure	Time frame
Onset of edema	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026