Clinical trial to investigate the effect of candesartan on QOL and geriatric syndome in elderly hypertensive patients

Clinical trial to investigate the effect of candesartan on QOL and geriatric syndome in elderly hypertensive patients - Elderly hypertension QOL-study of UnIversity & Primary care in Tokyo (EQUIP) Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001890

Enrollment

1000

Registered

2009-04-20

Start date

2009-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

essential hypertension

Interventions

Candesartan will be replaced with calcium channel blockers (Group A), or will be added to calcium channel blockers (Group B), depending on the blood pressure control as decided by attending physician.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Hypertensive patients who are taking calcium channel blockers for more than 4 weeks. 2) Outpatients 3) Those who show any impairment in SF-8 questionnaire.

Exclusion criteria

Exclusion criteria: 1) Subjects with irritation to candesartan 2) Subjects with (possible) pregnancy 3) Subejects with renal artery stenosis 4) Subjects with hyperkalemia 5) Subjects taking any angiotensin receptor blockers 6) Subjects who are unable to fill out the questionnaire 7) Other ineligible subjects

Design outcomes

Primary

Measure	Time frame
Changes of QOL questionnaire score (SF-8)	—

Secondary

Measure	Time frame
1) Subjective symptoms of the geriatric syndrome questionnaire. 2) Office blood pressure and pulse rate. 3) Home blood pressure and pulse rate	—

Countries

Japan

Contacts

Public ContactMasahiro Akishita

University of Tokyo Hospital Department of Geriatric Medicine

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026