The study of the usefulness of beta-blocker for hypertensive patients with persistent atrial fibrillation combined with reduced cardiac function

The study of the usefulness of beta-blocker for hypertensive patients with persistent atrial fibrillation combined with reduced cardiac function - The study of the usefulness of beta-blocker for hypertensive patients with persistent atrial fibrillation combined with reduced cardiac function

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001848

Enrollment

Registered

2009-04-04

Start date

2009-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertensive patients with persistent atrial fibrillation combined with reduced cardiac function

Interventions

Changing of beta-blocker

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with an inadequate heart rate control with carvedilol administration over one month

Exclusion criteria

Exclusion criteria: Patients with class III or IV of NYHA classification

Design outcomes

Primary

Measure	Time frame
1. Subjective symptom: Frequency of palpitation 2. Objective symptom: New York Heart Association (NYHA) classification of cardiac performance, BP, HR 3. Laboratory test: Blood biochemical findings include BNP, NT-proBNP, Urinalysis 4. Physiological laboratory: ambulatory electrocardiography, cardiac ultrasonography 5. Adverse event	—

Countries

Japan

Contacts

Public ContactSatoshi Kunimoto

Nihon University School of Medicine Division of cardiology, Department of medicine

kunimoto@med.nihon-u.ac.jp03-3972-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026