Esophageal cancer
Conditions
Interventions
Chemoradiaion(Docetaxel+RT)
Sponsors
National Cancer Center Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: patients must fulfill all of the following criteria to be eligible for the trial 1 thoracic esophageal cancer 2 histologically confirmed squamous cell carcinoma or adenocarcinoma or adenosquamous carcinoma 3 clinical stage from II to III except T4 4 patient do not receive any previous therapy for esophageal cancer and previous chemotherapy for any other malignancy 5 age from 70 to 80 years 6 ps of 0 and 1 7 patient do not want to receive esophagectomy 8 adequate organ funcion 9 no evidence to need treatment of ECG within 28 days prior to entering this study 10 written informed consent
Exclusion criteria
Exclusion criteria: patients who fulfill any of the following criteria are not eligible for the study 1 esophageal fistula 2 severe comorbidity 3 active infection 4 history of previous radiotherapy to thorax 5 chest Xray shows obvious interstitial pneumonia and pulmonary fibrosis 6 history of any other malignancy which is including synchronal double cancer or double cancer of disease free for less than 5 years but they are not including the carcinoma in situ or intramucosal cancer diagnosed as cure by local procedure 7 motor paralysis or peripheral neuropathy or edema 8 active men and women unwilling to practice effective contraception 9 evidence of psychological disease and symptom that may affect patient compliance with the study 10 patient who is judged as an inappropriate case by the doctor in charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 2-years survival | — |
Secondary
| Measure | Time frame |
|---|---|
| Complete Response Rate, Progression free survival, Adverse Events, Late Adverse Events | — |
Countries
Japan
Contacts
Public Contactken kato
National Cancer Center Hospital Gastrointestinal Oncology
Outcome results
None listed