Patients attending the outpatient clinic at Kyorin University Hospital or other facilities participating in this project, who are at or over the age of 65 years
Conditions
Interventions
Term: one year Drug: vitamin D (one alpha) Dose: 0.5 ug/day Frequency: every morning
Term: one year Drug: precipitated calcium carbonate (caltan) Dose: 500 mg/day Frequency: every morning
Sponsors
Department of Geriatric Medicine, Kyorin University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients at or over the age of 65 years, who are attending Kyorin University Hospital or other facilities participating in this project, who have a history of falling within one year, and whose creatinine clearance is less than 65mL/min by the Cockcroft-Gault formulas. All subjects or their family must give a written informed consent, especially in case of demented patients.
Exclusion criteria
Exclusion criteria: 1. Bed-ridden patient 2. Patient who has severe liver, GI-tract, or heart disease 3. Parkinson's disease 4. User of a wheel-chair 5. Patient who has paralysis 6. Patient who have a past history of treatment with vitamin D within 6 months 7. Inflammatory degenerative joint disease such as rheumatoid arthritis or osteoarthritis 8. Demented patient who is unable to evaluate a history of falling 9. Patient who has a past history of hypercalcemia or urolithiasis 10. Ineligible patient determined by the attending doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of falls after 6 months and 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone mineral density, bone metabolism markers, neuropsychological function, Fall-related factors such as muscle strength, fall-predicting score | — |
Countries
Japan
Contacts
Public ContactKoichi Kozaki
Kyorin University School of Medicine Department of Geriatric Medicine
Outcome results
None listed