Skip to content

Ocular hypotensive effects of tafluprost and travoprost in normal tension glaucoma; open-label,multi center, cross-over study

Ocular hypotensive effects of tafluprost and travoprost in normal tension glaucoma; open-label,multi center, cross-over study - Ocular hypotensive effects of tafluprost and travoprost in normal tension glaucoma

Status
Unknown
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000001829
Enrollment
100
Registered
2009-04-01
Start date
2009-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Normal Tension Glaucoma

Interventions

Tafluprost or travoprost monotherapy 12 weeks treatment once daily. Switching monotherapy from travoprost to tafluprost, or from tafluprost to travoprost 12 weeks treatment once daily

Sponsors

Mizoguchi Eye Clinic
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1: Patients with normal tension glaucoma 2: Untreated or over 4 weeks washout in treated with IOP-lowering medications.

Exclusion criteria

Exclusion criteria: 1: Patients with exfoliation glaucoma and neovascular glaucoma. 2: Patients with diabetic retinopathy. 3: Patients with advanced visual field loss(MD <-15dB). 4: Excessive myopia (<-6D). 5: Any corneal abnormality or other condition preventing reliable applanation tonometry. 6: Presence of any external disease and inflammation of the eye. 7: History of refractive surgery. 8: History of laser trabeculoplasty, filtering surgery, trabeculotomy, cataract surgery, and other intraocular surgery. 9: Pregnant, pregnant suspect, and nursing woman. Woman who is wishing pregnancy or is not able to prevent pregnancy. 10: The investigator declares any subject ineligible for any sound medical reason.

Design outcomes

Primary

MeasureTime frame
Intraocular pressure reduction, % reduction of intraocular pressure

Secondary

MeasureTime frame
Safety

Countries

Japan

Contacts

Public ContactTakanori MIzoguchi

MIzoguchi Eye Clinic Ophthalmology

t-mizo@siren.ocn.ne.jp0956-22-25681

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026