acute gastroenteritis
Conditions
Interventions
simple oral ondansetron prior to oral rehydration therapy (ORT) by WHO method
simple domperidon suppository pior to ORT by WHO method
Sponsors
Metropolitan clinical research network for acute illness in children
J-CRSU
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. having vomitting episode within 4 hours 2. bloody, biliary vomiting within 24 hours. 3. no nausea or vomiting episodes before 24 hours to one week 4. at least one moderate symptom and less than two severe symptom in Stephan B Freedman's dehydration score. in case over 24 months old, 'tears' symptom is not assessible one. 5. no following symptoms. decreased contious level, irritable, decreased acitivity 6. 6 months old to 10 years old 7. 8kg body weight or more 8. having chronic diseases 9. no history of abdominal open surgery 10. no use of steroid within a week 11. no use of antiemetics within 24 hours 12. no cough episodes which is possible to induce vomiting 13. written informed conscent
Exclusion criteria
Exclusion criteria: none
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| proportion of children having vomiting episodes during ORT | — |
Secondary
| Measure | Time frame |
|---|---|
| -Proportion of children excervated on dehydration status -Number of vomiting episode -Volume of oral rehydration salt -Proportion of need for intravenous fluid / administration -Adverse events -(Revisit rates) -problems of ORT education at outpatients section | — |
Countries
Japan
Contacts
Public ContactYoshihiko Morikawa
Metropolitan clinical research network for acute illness in children coodinating office
Outcome results
None listed