Gamma knife treatment results for patients with multiple brain metastases: A multi-institutional prospective study

Gamma knife treatment results for patients with multiple brain metastases: A multi-institutional prospective study - Multi-institutional prospective study of gamma knife surgery for brain metastases

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000001812

Enrollment

1200

Registered

2009-03-30

Start date

2009-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metastatic brain tumor

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) a maximum of 10 tumors 2) maximum diameter 30 mm or maximum tumor volume of 10 cc 3) no evidence of CSF dissemination on MRI 4) maximum total tumor volume of 15 cc 5) any histological diagnosis of primary tumor except sarcoma or lymphoma 6) KPS>=70 of KPS<70 due to neurological symptom 7) no past history of cranial radiation therapy or craniotomy

Exclusion criteria

Exclusion criteria: 1) active double cancer 2) in pregnancy or lactation period 3) psychiatric disorder 4) Allergy to gadolinium contrast or contraindication of MR imaging

Design outcomes

Primary

Measure	Time frame
Overall survival	—

Secondary

Measure	Time frame
Local tumor control, functional preservation, KPS, MMSE, distant recurrence, additional treatment	—

Countries

Japan

Contacts

Public ContactToru Serizawa

Tsukiji Neurological Clinic Tokyo Gamma Unit Center

gamma-knife.serizawa@nifty.com03-6226-3546

Outcome results