obsessive-compulsive disorder(OCD)
Conditions
Interventions
Fluvoxamine, up to a dose of 200mg/day, Autogenic Training (a psychological placebo), once a week for 12 weeks
pill placebo behavior therapy, once a week for 12 weeks
pill placebo Autogenic Train
Sponsors
Kyushu University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria for patients were aged from 18 to 60 years old and primary OCD diagnosis that was confirmed by the psychosis subsection of the structured clinical interview of DSM-IV.
Exclusion criteria
Exclusion criteria: comorbid axis I diagnosis neurological disorder head injury serious medical condition history of drug/alcohol addiction a total y-BOCS score lower than 16 a HDRS score more than 18 points a total IQ of less than 80
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Yale-Brown Obsessive Compulsive Scale (Y-BOCS) (after the 12-week treatment) functional activation maps (before and after treatment) Neuropsychological tests (attention, executive function, memory) | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Depressive Rating Scale (HDRS) State-Trait Anxiety Inventory (STAI) (after the 12-week treatment) | — |
Countries
Japan
Contacts
Public ContactTomohiro Nakao
Graduate School of Medical Sciences, Kyushu University Department of Neuropsychiatry
Outcome results
None listed