Randomized trial of transbronchial biopsy using endobronchial ultrasonography with guide sheath (EBUS-GS) and navigation by virtual bronchoscopy or X-ray fluoroscopy for pulmonary peripheral lesions

Randomized trial of transbronchial biopsy using endobronchial ultrasonography with guide sheath (EBUS-GS) and navigation by virtual bronchoscopy or X-ray fluoroscopy for pulmonary peripheral lesions - Randomized trial of transbronchial biopsy using EBUS-GS and VBN or X-ray fluoroscopy for pulmonary peripheral lesions

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001710

Enrollment

140

Registered

2009-02-16

Start date

2009-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

peripheral pulmonary lesions

Interventions

With navigation by virtual bronchoscopy With X-ray fluoroscopy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Peripheral pulmonary lesions of 30 mm> deemed, but not determined, as lung cancer 2.Not visible by bronchoscopy 3.20 or more than 20 years of age 4.SpO2 90% or more than 90% 5.Written informed consent

Exclusion criteria

Exclusion criteria: 1.Visible by bronchoscopy 2.GGO 3.Lesions deemed as benign diseases on chest CT 4.Severe complication 5.Disability of cessation of anticoagulant or antiplatelet more than 2 days 6.Pregnancy

Design outcomes

Primary

Measure	Time frame
Yield (Diagnostic rate)	—

Secondary

Measure	Time frame
1)The time to reach the lesion 2)The time of first biopsy 3)The time of X-ray fluoroscopy 4)The time of total examination 5)Agreement between bronchi by virtual bronchoscopy and actual bronchi 6)Bronchial generation inserted by bronchoscopy 7)Bronchial generation observed by bronchoscopy 8)Complication 9)Pain degree subscale	—

Countries

Japan

Contacts

Public ContactFumihiro Asano

Gifu Prefectural General Medical Center Department of Pulmonary Medicine

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026