Efficacy of Low-Dose hANP Administration in Patients Undergoing Emergent Coronary Artery Bypass Grafting for Acute Coronary Syndrome

Efficacy of Low-Dose hANP Administration in Patients Undergoing Emergent Coronary Artery Bypass Grafting for Acute Coronary Syndrome - NU-HIT trial for ACS

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000001654

Enrollment

200

Registered

2009-01-23

Start date

1997-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute myocardial infarction, unstable angina

Interventions

Perioperative administration of hANP Perioperative non-administration of hANP

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients Undergoing Emergent isolated Coronary Artery Bypass Grafting for Acute Coronary Syndrome Patients from whom informed consent was obtained

Exclusion criteria

Exclusion criteria: Patients Undergoing hemodialysis

Design outcomes

Primary

Measure	Time frame
cardiac event free rate	—

Secondary

Measure	Time frame
hemodynamics ANP, renin, anigotensin-II, aldsterone Incidence of arrhythmia mortality lon-term results after surgey complication cardioac function(UCG), BNP	—

Countries

Japan

Contacts

Public ContactAkira Sezai

Nihon University School of Medicine Department of Cardiovascular Surgery

asezai.med@gmail.com03-3972-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026